PPT Slide

5

10

Ave.

E.g. Half-sib family - Sire mated at random

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Sire

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Half-sib

Progeny

1/2(1-r)=.4

1/2(1-r)=.4

1/2 r =.1

1/2 r =.1

(.4*10+.1*5)/.5 = 9

Contrast mM?-mm?

= 3 = (1-2r)a

(1-2*.2)(10-5)

r =.2

Non-recombinants

Recombinants

10

5

(.4*5+.1*10)/.5 = 6

Population-wide vs within family Linkage Disequilibrium

Linked loci are in linkage DISequilibrium within families despite population-wide Equilibrium

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