PPT Slide

Interval Mapping

To estimate QTL position and effect

separately

Q

q

M

m

r1

N

n

r2

q

Backcross

q

q

m

m

n

n

m+d

X

Q

M

1/4(1-r1)(1-r2)

N

m -a

q

M

1/4 r1 r2

N

m+d

Q

M

1/4(1-r1) r2

n

m -a

q

M

1/4 r1 (1-r2)

n

m+d

Q

m

1/4 r1 (1-r2)

N

m -a

q

m

1/4(1-r1) r2

N

m+d

Q

m

1/4 r1 r2

n

m -a

q

m

1/4 (1-r1)(1-r2)

n

Frequency

value

XM XN Prob(Q|marker data)=XQ

QTL position

1 1 (1-r1)(1-r2)/(1-q)

1 0 (1-r1) r2 /q

0 1 r1 (1-r2)/q

0 0 r1 r2 /(1-q)

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